STRADEFY BIOSCIENCES
Pioneering next-generation Bioadhesive Drug Carriers (BDCs)
Pioneering next-generation Bioadhesive Drug Carriers (BDCs)
Stradefy Biosciences is pioneering next-generation bioadhesive drug carriers (BDCs), rationally engineered for cellular bioadhesion, uptake and therapeutic payload release, at levels well beyond seen with antibody drug conjugates (ADCs). Lead candidates, initially targeting unmet needs in the oncology and immunology areas, have demonstrated in vivo proof of efficacy and are advancing to the IND stage.
Based in New Haven, CT, Stradefy was co-founded by Mark Saltzman, Michael Girardi, Yale University and Elm Street Ventures.
BDC's maximize the efficacy of active drug product by optimizing retention and internalization in target tissues and cells. They are analogous to ADCs with higher active drug loads and differentiated retention and cell internalization.
Our lead candidate has demonstrated efficacy in multiple oncology models. We have a capital efficient path to obtain proof of concept in targeted oncology.
Stradefy is based on the research of Mark Saltzman and Mike Girardi at Yale University, and has strong patent protection.
Academic Founder
Goizueta Foundation
Professor of Chemical and Biomedical Engineering
Yale University
Academic Founder
Vice Chair & Evans Prof of Dermatology
Yale School of Medicine
Executive Chair
Jeff Goldberg is Executive Chair of Stradefy Biosciences and an advisor to several other therapeutics companies. Previously, he served as CEO of Aeglea
BioTherapeutics, CEO of Immunitas Therapeutics, and COO of Akcea Therapeutics.
Venture Partner
Brian is a Venture Partner at Elm Street Ventures. Prior to ESV he was CEO of BioRelix, Inc., and prior to that he directed drug discovery, DPMK, and other key R&D activities at Bayer.
If you are interested in learning more about our work, we'd love to hear from you. Please contact Jeff Goldberg, Executive Chair, at the form below.
Stradefy Biosciences
Copyright © 2025 Stradefy Biosciences - All Rights Reserved.
We use cookies to analyze website traffic and optimize your website experience. By accepting our use of cookies, your data will be aggregated with all other user data.